Search on: COMPLEMENT INACTIVATOR PROTEINS 
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Descriptor English:   Complement Inactivator Proteins 
Descriptor Spanish:   Proteínas Inactivadoras de Complemento 
Descriptor Portuguese:   Proteínas Inativadoras do Complemento 
Tree Number:   D12.776.124.486.274.920
Definition English:   Serum proteins that negatively regulate the cascade process of COMPLEMENT ACTIVATION. Uncontrolled complement activation and resulting cell lysis is potentially dangerous for the host. The complement system is tightly regulated by inactivators that accelerate the decay of intermediates and certain cell surface receptors. 
Indexing Annotation English:   do not confuse with COMPLEMENT INACTIVATING AGENTS; DF: COMPLEMENT INACT
Pharmacological Action:   Complement Inactivating Agents
 
History Note English:   2006 (1978) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   22145 
Unique Identifier:   D003169 

Occurrence in VHL:
 

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